As estrogen levels decline, joint lubrication reduces, and oxidative stress increases. This hormonal shift also leads to unexpected weight gain, particularly around the abdomen. Understanding these changes is crucial for managing the multifaceted effects of lower estrogen on women's health. As estrogen levels drop, the resulting changes take a toll on joint tissues, damaging cartilage and bones. This "Triple Threat" from hormonal decline causes significant discomfort and restricts movement, underscoring the need for awareness and intervention.