The AgeAura NMN + TMG ingredients are seven actives in a 2-capsule US serving: 500 mg NMN, 250 mg TMG, 150 mg quercetin, 100 mg trans-resveratrol, 50 mg apigenin, 400 mcg DFE folate and 1 mg spermidine. Each one has some human or lab data on its own. No human trial has tested this exact combination.
This page walks through the AgeAura Supplement Facts panel line by line. For each ingredient, you get what studies in people found, and what is still not proven. It does not repeat our other guides. For the reason NMN and TMG are paired, read why NMN and TMG are taken together. For trial doses, read how much NMN per day.
The AgeAura Label at a Glance (US Formula)
| Ingredient (per 2 capsules) | Amount | Human evidence on its own | What is not proven |
|---|---|---|---|
| NMN (β-nicotinamide mononucleotide) | 500 mg | 10-week RCT: better muscle insulin sensitivity in women with prediabetes | Effects in healthy adults, long-term outcomes |
| TMG (betaine anhydrous) | 250 mg | Lowers homocysteine at 4–6 g/day | Any effect at 250 mg |
| Quercetin (Sophora japonica) | 150 mg | Small blood pressure drop at 500 mg/day or more | Any effect below 500 mg/day |
| Trans-resveratrol (Polygonum cuspidatum) | 100 mg | Little or no metabolic benefit in overweight adults | A clear benefit in healthy people |
| Apigenin | 50 mg | None found in people for NAD+ | CD38 data are from cells and mice only |
| Folate (as L-5-MTHF) | 400 mcg DFE | Needed for homocysteine recycling; 400 mcg DFE is the adult RDA | Benefit beyond a normal diet |
| Spermidine (wheat germ extract) | 1 mg | 12-month RCT at 0.9 mg/day: no significant memory change | A memory or aging benefit |
Sources: AgeAura product page, Yoshino 2021, McRae 2013, Serban 2016, Linus Pauling Institute: resveratrol, Escande 2013, Linus Pauling Institute: folate, Schwarz 2022.
NMN: 500 mg
NMN is the main ingredient. Its best-known human result is a 2021 randomized, placebo-controlled, double-blind trial in Science. In postmenopausal women with prediabetes who were overweight or obese, 10 weeks of NMN increased muscle insulin sensitivity and signaling.
What is not proven: that result came from one group of women with a metabolic problem. It does not show that NMN slows aging in healthy adults. Trial doses are covered in our NMN dose guide.
TMG (Betaine): 250 mg
TMG is betaine. It gives a methyl group to homocysteine and turns it back into methionine. A 2013 meta-analysis of 5 trials in healthy adults found that at least 4 g a day of betaine for 6 to 24 weeks lowered homocysteine by 1.23 μmol/L on average.
A 2002 trial in 42 obese adults gave 6 g a day for 12 weeks. Homocysteine went down, but body weight and body composition did not change. LDL cholesterol was higher in the betaine group.
What is not proven: those trials used 4 to 6 g. The AgeAura label has 250 mg, which is far below that range. Read it as a methyl-support ingredient, not a homocysteine treatment.
Folate as L-5-MTHF: 400 mcg DFE
Folate works next to TMG. The enzyme methionine synthase needs folate, in the form 5-methyltetrahydrofolate, plus vitamin B12 to convert homocysteine to methionine. When folate is low, homocysteine builds up.
The adult RDA is 400 μg DFE a day (600 in pregnancy, 500 while breastfeeding). The label dose matches the adult RDA. The upper limit of 1,000 μg a day applies to folic acid from supplements and fortified foods, so count any multivitamin you already take.
What is not proven: a benefit beyond normal folate status.
Trans-Resveratrol: 100 mg
Resveratrol is the most-studied extra. The Linus Pauling Institute reviewed the trials and found little or no metabolic benefit in overweight or obese people who did not already have a clear metabolic problem. Our NMN and resveratrol guide covers the trials in detail.
What is not proven: a clear benefit in healthy adults.
Quercetin: 150 mg
A 2016 meta-analysis pooled 7 trials with 587 patients. Quercetin lowered systolic blood pressure by 3.04 mmHg and diastolic by 2.63 mmHg. The effect showed up mainly at 500 mg a day or more. Below 500 mg a day, it was not significant.
What is not proven: any blood pressure effect at 150 mg.
Apigenin: 50 mg
Apigenin is on the label because of a 2013 lab study. Apigenin and quercetin inhibited CD38, an enzyme that uses up NAD+, and raised NAD+ in cell cultures and obese mice.
What is not proven: that this happens in people. We found no human trial of apigenin for NAD+.
Spermidine: 1 mg (From Wheat Germ)
The SmartAge trial gave 100 adults aged 60 to 90 with self-reported memory decline 0.9 mg a day of spermidine from wheat germ, or placebo, for 12 months. Memory did not change significantly (P = .47). Side effects were similar in both groups.
What is not proven: a memory or aging benefit.
What Is Not Proven About the Full Formula
We searched for a randomized human trial of NMN with betaine, resveratrol, quercetin, apigenin or spermidine. We found reviews, not trials. So nobody has shown that this combination works better than NMN alone. Also, three ingredients (TMG, quercetin, spermidine) sit below or near the doses where human trials looked.
✅ Read the Supplement Facts panel, not the front label: 7 actives, 2 capsules per serving.
✅ Count folate from any multivitamin you already take.
✅ Ask your clinician first if you take a blood thinner or an NSAID (resveratrol caution).
✅ Note the wheat: spermidine comes from wheat germ extract.
Is AgeAura Legit? Who Makes It
AgeAura is sold by Wellness Nest at wellnessnest.co, where it sits in the best sellers collection. The product page states that it is made in a USA cGMP-certified partner facility, with non-GMO vegan capsules. It also says batch documentation will be published on the page when it is available, so third-party test results are not posted yet.
Two reviews on the product page are measured, not hype. Rachel, 46, a night-shift nurse, wrote that she no longer gets the wired feeling and sleeps a bit better: "Nothing I'd call life-changing." Tom, 58, did a 90-day stop test: "When I stopped I noticed I was more tired and flatter again."
Does AgeAura Contain Gluten or Wheat?
The label says both things, and both are on the product page. It lists "Free from: gluten, soy, dairy, fish & shellfish." It also lists "Contains: Wheat (spermidine from wheat germ extract)." If you have a wheat allergy or celiac disease, ask your clinician before you take it.
How to Take It and Who Should Not
The label serving is 2 capsules at the same time each morning, often with the first meal. If you fast, take them with water when you break the fast. If sleep feels off, move the dose earlier. The page lists mild stomach sensitivity or a change in sleep timing as possible effects. For NMN-specific checks, read NMN side effects: 6 checks before you start.
Talk to a provider first if you are pregnant or nursing, under 18, take any medication, or manage a health condition.
Where to Buy AgeAura NMN + TMG in the US
The official source is Wellness Nest at wellnessnest.co. AgeAura Pure NMN + TMG NAD+ Complex is $69.95, with free US shipping over $70 and a 90-day refund policy (eligibility applies). You can also browse the store's best sellers.
See the AgeAura Supplement Facts panel →
Frequently Asked Questions
What are the ingredients in AgeAura NMN + TMG?
Per 2-capsule serving, AgeAura lists 500 mg NMN, 250 mg TMG (betaine anhydrous), 150 mg quercetin, 100 mg trans-resveratrol, 50 mg apigenin, 400 mcg DFE folate as L-5-MTHF and 1 mg spermidine from wheat germ extract. The capsule is vegetable cellulose. Each ingredient has some research on its own, but no human trial has tested the full combination.
Is AgeAura legit?
AgeAura is sold by Wellness Nest at wellnessnest.co, which states it is made in a USA cGMP-certified partner facility. The product page shows a 90-day refund policy and says batch documentation will be posted when available. Reviews on the page are modest, for example "Nothing I'd call life-changing." Judge it by the label and the evidence, not by hype.
How many AgeAura capsules a day?
The label serving is 2 capsules a day, taken together at the same time each morning, often with your first meal. If you fast, take them with water when you break the fast. If your sleep feels off, move the dose earlier in the day. Do not take more than the label serving unless your clinician tells you to.
Does AgeAura contain gluten or wheat?
The label says it is free from gluten, soy, dairy, fish and shellfish. It also says it contains wheat, because the spermidine comes from wheat germ extract. If you have a wheat allergy or celiac disease, talk to your clinician before you take it. Both statements appear on the official product page at wellnessnest.co.
Who should not take AgeAura?
The label tells you to talk to a provider first if you are pregnant or nursing, under 18, taking any medication, or managing a health condition. The resveratrol in it carries a caution for blood thinners and NSAIDs. People with a wheat allergy should also check first, because the spermidine is from wheat germ extract.
About the Author
Dr. Marcus Hale — Dr. Marcus Hale is the resident health researcher behind Wellness Nest's editorial team, translating peer-reviewed sports-nutrition and longevity research into practical daily guidance for US readers.
